Consider the situation where the person responsible for something has fallen behind and, although they haven't reached burnout, plodding through the guilt is taking up so much of their effort that they make very little progress and fall further behind.

(I see myself in this comment and don't like it.)

Yeah, absolutely a common syndrome, that I've been through more than once myself. Indeed, I'm currently trying to remove several of my hats (across several organizations) in order to get it under control.